�Isolagen(TM), Inc. (Amex:
ILE) announced results from a prospective, open label, Phase II study
(IT-R-007) of Isolagen Therapy(TM) for the treatment of facial wrinkles and
creases in more or less 40 subjects. Study subjects received two
treatments of Isolagen Therapy in multiple facial regions ("full face")
approximately quintet weeks apart. The cogitation results reported improvement in
the appearance of wrinkles as scored by a high percentage both of study
subjects as substantially as of independent panel evaluators. The study results also
reported improvement in skin quality as scored by a high part of both
study subjects and participating investigators.
Six months next their final treatment ("the six-month metre
point"), 83 percent of subjects reported an improvement in their
self-assessed score of the appearance of their wrinkles. This scale was the
same as the one used in the latterly completed Isolagen Therapy polar
efficacy studies (IT-R-005 and -006). At the six-month time point, the
results from the independent jury evaluation of study photographs also
showed improvement in the appearance of wrinkles, with the independent
dialog box scoring betterment in over 75 per centum of participants.
"We ar very pleased with the outcome of this exploratory study," said
Declan Daly, President and Chief Executive Officer of Isolagen. "We are
especially interested in the responses around pelt quality, as this is
the first time we have assessed the Isolagen Therapy for these crucial
skin characteristics."
Study IT-R-007 Study Results
As seen in all previous studies of Isolagen Therapy, treatment was very
well tolerated in Study IT-R-007. No serious adverse events related to the
Isolagen Therapy were observed.
Efficacy results from the trial showed that 83 pct of bailiwick
subjects reported improvement in the appearance of their wrinkles using a
subject assessed, five-point response scale that ranged from "identical
dissatisfied" to "very quenched." Improvement was defined as a one point
move on the scale. The subject judgement scale is the same scale used in
the recently realized IT-R-005 and 006 pivotal Phase III studies of
Isolagen Therapy.
The sketch results as well included assessments from an independent panel
of trey aesthetic dermatologists and plastic surgeons world Health Organization were not
involved with the treatment of subjects in the study. Results from these
independent evaluations noted improvement in the appearance of wrinkles in
more than 75 percent of study subjects using an evaluator-assessed,
four-point scale developed for this report, ranging from "no improvement" to
"marked improvement." Improvements were assessed using photographs of
subjects taken at baseline and at the six-month time point.
Study IT-R-007 also included an assessment of skin quality of the study
subjects, comparing results from baseline to the final six-month visit.
Using a Skin Quality Assessment Tool developed for this study, 93 percent
of subjects aforementioned their peel quality improved. Additionally, more than 95
percent of subjects showed improvements in skin quality based on the
Treating Investigator Assessment. Subjects and treating investigators each
assessed eight skin characteristics ordinarily seen as the face ages and
solar damage increases. Skin quality characteristics assessed at baseline
and the final six-month see were: softness, suppleness, eloquence,
firmness, thickness, moistness, evenness in appearing and invigorated
appearance. While the Skin Quality Assessment tool is not validated,
Isolagen is evaluating this scale for future function.
"As the principal investigator in the Isolagen IT-R-007 trial, I am
optimistic about the study results which show improvement in patients'
facial appearance," said Dr. Girish Munavalli, Assistant Professor of
Dermatology at Johns Hopkins School of Medicine. "The results intimate that
improvements in both skin texture and contour may be achieved following
Isolagen treatment. I believe this final result is a unique determination in the
cosmetic injectable treatment market, utilizing the subject's have living
cells to bring home the bacon the basis for advance."
Conducted at five US sites, the primary objectives of Study IT-R-007
were to assess the base hit and efficacy of the Isolagen Therapy. In this
open label study, all subjects received the Isolagen Therapy and there was
no placebo control.
The Isolagen Process(TM) is a proprietary cellular processing organisation
that creates a natural, living cell therapy. By multiplying a person's own
collagen-producing cells, or fibroblasts, into tens of millions of new
cells, a personalized discourse is created that is then returned to the
person's skin. This first of its kind aesthetical treatment, known as the
Isolagen Therapy, is intentional to better skin damage caused by the normal
effects of aging, sunday damage, acne and burns.
About Isolagen, Inc.
Isolagen(TM), Inc. (Amex: ILE) is an aesthetic and therapeutic companionship
committed to developing and commercializing scientific advances and
innovative technologies. The company's technology political platform includes the
Isolagen Process(TM), a cubicle processing system for hide and tissue
rejuvenation which is presently in clinical development for a broad range
of aesthetic and therapeutic applications including wrinkles, acne scars,
burns and periodontal disease. Isolagen too commercializes a
scientifically-advanced line of skincare systems through its majority-owned
subsidiary, Agera(R) Laboratories, Inc. For additional information, please
visit http://www.isolagen.com.
Isolagen Forward Looking Statements
All statements in this news release that are non based on historical
fact are "forward-looking statements" inside the import of the Private
Securities Litigation Reform Act of 1995 and the viands of Section 27A
of the Securities Act of 1933, as amended, and Section 21E of the
Securities Exchange Act of 1934, as amended. While management has based any
forward-looking statements contained herein on its current expectations,
the information on which such expectations were based may variety. These
forward-looking statements bank on a number of assumptions concerning
future events and ar subject to a number of risks, uncertainties, and
other factors, many of which are outside of our ascendence, that could cause
actual results to materially differ from such statements. Such risks,
uncertainties, and other factors include, but are not of necessity limited
to, those rig forth under Item 1A "Risk Factors" in the Company's Annual
Report on Form 10-K for the year ended December 31, 2007, as updated in
"Item 1A. Risk Factors" in the Company's Quarterly Reports on Form 10-Q. We
operate in a highly competitive and speedily changing environment, thus new
or unlooked-for risks crataegus laevigata arise. Accordingly, investors should not place any
trust on advanced statements as a prediction of actual results.
We disclaim whatever intention to, and set about no responsibility to, update or
retool any innovative statements. Readers are also urged to carefully
limited review and consider the other various disclosures in the Company's Annual
Report on Form 10-K for the year complete December 31, 2007, as well as other
public filings with the SEC since such date.
Isolagen(TM), Inc.
http://www.isolagen.com
More information
Saturday 6 September 2008
Thursday 28 August 2008
Download Govi mp3
 Artist: Govi: mp3 download Genre(s): New Age Latin: Flamenco Ethnic Instrumental Discography:  Jewel Box Year: 2006 Tracks: 10  Saffron and Silk Year: 2004 Tracks: 9  Mosaico Year: 2002 Tracks: 10  Your Lingering Touch Year: 2001 Tracks: 12  Seventh Heaven Year: 2000 Tracks: 10  No Strings Attached Year: 1999 Tracks: 10  Andalusian Nights Year: 1999 Tracks: 9  Passion and Grace Year: 1995 Tracks: 8  Cuchama Year: 1993 Tracks: 9  Heart Of A Gypsy Year: 1987 Tracks: 9  Sky High Year: 1986 Tracks: 6  Your Lingering Touch: Govi At His Romantic Best Year: Tracks: 12 This California-based guitar player was really born in Germany. His intake and vogue ar similar to that of another German immigrant, Deuter, wHO co-produced and performed on Govi's debut record album Sky High. Like Deuter, Govi spent a number of days living and perusal in India, where he added sitar to his vocabulary of acoustic and electrical guitars, mandola, and cello.Govi's music gained in popularity in the 1990s, with the enlargement of peoples sentience of world medicine and a renewed rage for gypsy dancing, spawning novel age strike albums like Andalusian Nights and Passion and Grace. His medical specialty is a easy, melodious combination of influences from round the world. |
Sheryl Crow and Rock the Vote Team Up for Voter Registration Drive
Monday 18 August 2008
Los Campesinos! Announce Autumn UK Tour
Los Campesinos! have proclaimed details of a UK tour in support of their new album 'We Are Beautiful, We Are Doomed'.
The circuit kicks turned in Brighton on October 14th and concludes in Manchester on October 22nd.
The band's instant album is due to be released on October 13th.
Tickets for the circuit go on sale tomorrow (August 15th) at 9am and testament be usable through Gigwise here.
Alternatively, you can ring our ticket hotline on 0871 230 1098 for more information.
Los Campesinos! tour dates are:
Brighton, Komedia - October 14
Liverpool, Carling Academy 2 - 15
Leeds, Irish Centre - 16
Dublin, Whelans - 17
Glasgow, School of Arts - 18
London, Electric Ballroom - 20
Bristol, Fleece - 21
Manchester, Academy 3 - 22
Buy Los Campesinos! tickets
More information
Friday 8 August 2008
Brit pop conquers the world again
We've always been proud of our British pop that towers supra that produced by
our European neighbours, but for the yesteryear decade � when it comes to
worldwide gross revenue � we've come up against better-faring American artists.
But no longer, it seems. In a chart of this year's biggest-selling pop artists
in the world, four out of the basketball team best-selling acts of the Apostles hail from Britain.
Amy Winehouse's Back to Black, first released in 2006, sold 3.67 million
copies this year, pushing its total sales to almost 10 million.
Coldplay released Viva la Vida just last month, simply they have managed already
to shift 2.6 million copies, putting them in second base place. Leona Lewis sold
2.4 million copies of Spirit, putting her third, piece Duffy is in fifth
place after selling 2.25 1000000 copies of Rockferry.
The Welsh vocaliser left American rivals Madonna, Alicia Keys, Mariah Carey, Lil
Wayne and Michael Jackson's re-released Thriller trailing behind in the Top
10. Only Jack Johnson outsold her, pipping her to quarter place.
More info
Wednesday 18 June 2008
Foreigner
Artist: Foreigner
Genre(s):
Rock
Rock: Pop-Rock
Rock: Hard-Rock
Pop
Discography:
Foreigner - Complete Greatest Hits
Year: 2002
Tracks: 20
Definitive
Year: 2002
Tracks: 20
Mr. Moonlight
Year: 1999
Tracks: 11
Records
Year: 1995
Tracks: 10
Classic Hits Live
Year: 1993
Tracks: 14
The Very Best... and Beyond
Year: 1992
Tracks: 17
Unusual Heat
Year: 1991
Tracks: 11
Inside Information
Year: 1987
Tracks: 10
Agent Provocateur
Year: 1984
Tracks: 10
4
Year: 1981
Tracks: 10
Head Games
Year: 1979
Tracks: 10
Double Vision
Year: 1978
Tracks: 10
Foreigner
Year: 1977
Tracks: 10
Best of Ballads
Year:
Tracks: 17
While quite a few arena stone acts of the Apostles of the '70s establish the transformation into the '80s quite unmanageable, various acts continued to flourish and enjoyed some of their biggest commercial-grade success: Journey, Styx, REO Speedwagon, and particularly Foreigner. Foreigner's leader from the commencement has been British guitarist Mick Jones, world Health Organization low stony-broke into the euphony game as a "hired torpedo" of sorts, appearing on recordings by George Harrison and Peter Frampton, and as part of a later-day version of unvoiced bikers Spooky Tooth. By the mid-'70s, Jones had resettled to New York City, where he was a brief member of the Leslie West Band and served as an A&R man for a phonograph record company. But it wasn't long ahead Jones felt the press to be part of another rock outfit as he sought to place together a isthmus that would be able to combine elements of sway, progressive, R&B, and pop into a single, cohesive style.
Mother Jones presently assembled a group consisting of ex-King Crimson saxophone player Ian McDonald and ex-Ian Hunter drummer Dennis Elliot (both of whom were British), along with New York musicians Al Greenwood (keyboards), Ed Gagliardi (bass voice), and Lou Gramm (vocals), the latter of which was previously a member of an apart '70s outfit called Black Sheep. Jones set up immediate songwriting chemistry with Gramm (one of the first base songs they wrote together was the eventual arrive at "Cold As Ice"), resulting in the freshly formed band pickings the key out Foreigner and signing a recording contract with Atlantic Records. Foreigner's self-titled debut was issued in 1977 and became an immediate strike on the force of the arrive at singles "Feels Like the First Time," "Long, Long Way From Home," and the aforementioned "Cold As Ice," as the album would finally go atomic number 78 five-spot times all over.
Foreigner avoided the horrendous soph slump with an even stronger follow-up release, 1978's Double Vision, which spawned such further strike singles as "Hot Blooded" and its title track, and the album stayed in the Top Ten for a solid six-spot months. As a solution, the album's success established the sextet as an field headliner and would go on to become Foreigner's best-selling album of their career (selling sevener one thousand thousand copies in the U.S. lone by 2001). The group's third spill boilers suit, Head Games, followed in 1979 and pronounced the first base of many subsequent card changes for the group, as Gagliardi was replaced by ex-Peter Frampton and Roxy Music bassist Rick Wills. While the album was another big marketer and turned forbidden to be their virtually straight-ahead musically, both Gramm and Jones felt that the album failed to break any modern anchor, something that they sought to compensate on their next album.
The band's card was cut back to exactly a quartette consisting of Jones, Gramm, Elliot, and Wills as super-producer Mutt Lange (wHO was clean off the achiever of AC/DC's classical Back in Black) was enlisted to supervise the minutes. The gambit worked and the resulting 1981 spill, 4, was another massive trafficker, spawning such farther hit singles as "Pressing" (which featured a dazzling sax solo from Motown vet Junior Walker), "Nickelodeon Hero," and the mightiness ballad "Wait for a Girl Like You." Although the latter strain was a massive strike, it confounded some of the band's following as to whether Foreigner was a strong rock 'n' roll band or balladeers. In 1982, a stopgap best-of rig, Records, was released and featured ten-spot of band's biggest arrive at singles, left a steady vender to this day (comely Foreigner's second album to achieve gross revenue of seven-spot billion by 2001).
It took Foreigner triad days to discharge a review to 4 with Agentive role Provocateur existence issued in 1984. The band made the transition to the MTV video years without a preventative with the over-the-top, gospel-inflected ballad "I Want to Know What Love Is" (which featured the New Jersey Mass Choir) comme il faut one of the biggest MTV and radio set hits that year. But scorn the single's success, at that place was a noticeable douse in gross revenue for Agentive role Provocateur when compared to their sooner albums due to the fact that the album wasn't as focused and strong boilersuit as their premature recordings. After a mammoth nine-month term of enlistment mantled up a year later, both Jones and Gramm focused on non-Foreigner projects during 1986. Jones produced Bad Company's Renown and Fortune and co-produced Van Halen's strike debut recording with Sammy Hagar, 5150, spell Gramm worked on a solo debut. The sack of both Gramm's solo album, Ready or Not, as well as Foreigner's one-sixth studio album boilersuit, Inside Information, came in 1987. While both were successful and spawned Top Ten hits (Gramm with "Midnight Blue" and Foreigner with "Read You Will"), latent hostility between Gramm and Jones came to a head regarding the singer's desire to focus on his solo career, which lED to Gramm's split from Foreigner in 1989.
The same year as his split from Foreigner, Gramm issued his second solo album, Long Hard Look, which proved to be not as successful as its predecessor, spell Jones produced Billy Joel's Storm Front and issued a star-studded self-titled solo debut. Jones, Elliot, and Wills well-tried to keep Foreigner afloat with a raw singer, Johnny Edwards, issuance a for the most part neglected album in 1991, Unusual Heat, spell Gramm faired no better with a raw outfit, Shadow King, issuance a disregarded self-titled debut the same class. Seeing the error in their split, both Jones and Gramm listened to the advice of Atlantic Records and reunited for the recording of tercet all-new tracks to be included on a more extensive "hits" compendium. Issued in 1992, the 17-track The Very Best...And Beyond was Foreigner's most commercially successful tone ending in several years along with the band's commencement live spillage, Greco-Roman Hits Live, issued a yr later.
The Gramm/Jones reunion soon turned permanent and newfangled members Bruce Turgon (freshwater bass) and Jeff Jacobs (keyboards) were welcomed on board. The up-to-the-minute adaptation of Foreigner issued an all-new studio apartment recording in 1995, Mr. Moonlight, which failed to bring back the group to the tip of the charts. Foreigner remained a popular concert attraction, just the band's future was thrust into doubt in 1997 when Gramm was diagnosed with a brain neoplasm. Luckily, the neoplasm was non-cancerous and was removed short thenceforth. Gramm's recovery was dull and painful, just by 1999, the singer was well enough for Foreigner to team up with Journey for a summer term of enlistment. The early twenty-first century saw the release of several archival collections good manners of the Rhino label: a pair of extra collections, Nickelodeon Heroes: The Foreigner Anthology and Fill in Greatest Hits, as well as reissues of the group's self-titled debut and 4, both of which included extra incentive tracks.
New Kids on the Block add more dates
Monday 9 June 2008
Psyburbia
Artist: Psyburbia
Genre(s):
Trance: Psychedelic
Discography:
Interstellar Filtersweep
Year: 2003
Tracks: 7
Interstellar Filtersweep
Year: 2003
Tracks: 7
Tuesday 3 June 2008
Joey Youngman
Artist: Joey Youngman
Genre(s):
House
Discography:
Unconditional (Ep)
Year: 2007
Tracks: 3
Supercuts genre
Year: 2006
Tracks: 4
Joey's Waffle House EP
Year: 2005
Tracks: 3
Charlie Sheen - Sheen Weds Mueller In La Ceremony
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